Мы используем Cookies Этот веб-сайт использует cookie-файлы, чтобы предлагать вам наиболее актуальную информацию. Просматривая этот веб-сайт, Вы принимаете cookie-файлы.
The quaternary ammonium linker represents a significant advance in linker technology, enabling stable conjugation of payloads with tertiaryamine residues.
3
The tertiaryamine is then distilled off, the residual products separated by filtration and finally hydrolysed by a caustic alkali.
4
External to the aromatic site, there is another weaker and less gating-dependent site for the tertiaryamine chain in the latter two drugs.
5
The quaternary ammonium linker was then applied to a tubulysin antimitotic drug that contained an N-terminal tertiaryamine that was important for activity.
6
The mechanism whereby tertiaryamine local anesthetics affect the activity of membrane proteins was investigated by studying the interaction of phenothiazines with mitochondrial ATP synthase.
7
The simplest aromatic tertiaryamine, triphenylamine, is prepared by the action of brombenzene on sodium diphenylamine (C. Heydrich, Ber., 1885, 18, p. 2156).
8
The secondary and tertiaryamines do not give this reaction.
9
When heated with alkyl or aryl iodides, they are converted into secondary and tertiaryamines.
10
The mixed tertiaryamines are produced by the action of alkyl halides on the primary amines.
11
The tertiaryamines may also be of two types, the purely aromatic and the mixed type.
12
A new carbamoylation of tertiaryamines is reported.
13
The primary, secondary and tertiaryamines may be readily distinguished by their behaviour with various reagents.
14
The tertiaryamines possess the power of combining with one molecular proportion of an alkyl iodide to form quaternary ammonium salts.